Stroke in the Young Project
Ethnic disparities in stroke risk in children parallel those in adults, with blacks at twice the risk compared to whites. Early studies suggest that the increasing trend of stroke risk over the last decade is most dramatic among young blacks and Asians/Pacific Islanders.
Update: Data collection for pediatric stroke patients is complete and analysis of this dataset is ongoing. Data collection for young adult stroke patients is near complete. Data collection for the controls in the case-control study is currently ongoing.
The specific aim of Stroke in the Young is to conduct an observational cohort study of children, adolescents and young adults to identify trends over time in traditional and novel factors that may increase stroke risk in this age group.
The study will develop a highly sensitive and specific algorithm for using electronic data to identify ischemic stroke and atherosclerotic risk factors (such as hypertension, hyperlipidemia, diabetes mellitus, obesity, smoking) in a cohort of children and adults, and will validate this algorithm in a separate cohort.
In addition, a large, population-based cohort of children and young adults (< age 50) from Kaiser Permanente Northern California will be observed over a 15-year time period to determine overall trends in the incidence rate of ischemic stroke, and to evaluate the trend in stroke incidence rates among subgroups of race and gender.
Among a subcohort of Kaiser Permanente Northern California members hospitalized for stroke, investigators will determine overall trends in the prevalence of atherosclerotic risk factors, and evaluate trends in prevalence of these risk factors among subgroups of race and gender.
In a case-control study nested within the cohort of children and young adults, investigators will evaluate the role of socioeconomic status, atherosclerotic risk factors, trauma, sickle cell disease, and other stroke risk factors, in the ethnic disparities of stroke incidence.
Read more about our research »