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​​Shake, Rattle and Roll

"Shake, Rattle and Roll" reflects the trial's objectives of "shaking" the salt habit, "rattling" the intensity of the current clinical blood-pressure protocol, an​d designing interventions with the ultimate goal of being able to adapt and "roll" out best practices to the community, region and nation.​​

Update: Enrollment and the 1 ​year follow-up have been completed for all participants in Lifestyle, Enhanced Monitoring and Usual Care arms of the study. Preliminary data analysis is in progress.

The core research question for this cluster, pragmatic, randomized trial is whether a primary care prevention intervention of either diet and lifestyle coaching or an intensive pharmacotherapy protocol is more effective than usual care in improving rates of hypertension control in blacks.​

The study population includes all adults within enrolled clinical sites of Kaiser Permanente Northern California (Oakland Medical Center) with uncontrolled hypertension (systolic blood pressure ≥ 140 mg/Hg​ and/or diastolic blood pressure ≥ 90 mg/Hg).

By implementing these interventions, we aim to reduce the disparity in hypertension control rates between blacks and whites by 4 percent within 1 year of study enrollment.

An ancillary aim is to project the anticipated downstream effects on stroke, cardiovascular disease, death and quality-adjusted life years of observed blood pressure reductions using the Cardiovascular Disease (CVD) Policy Model – a computer model of stroke and cardiovascular ​

Investigators

Mai N. Nguyen-Huynh, MD, MAS  
Mai N. Nguyen-Huynh, MD, MAS
Principal Investigator
​​
Stephen Sidney, MD, MPH  
Stephen Sidney, MD, MPH
Co-Principal ​​Investigator
​​ ​​
Susan D. Brown, PhD  
Susan D. Brown, PhD
Co-Investigator
​​
Bette Caan, DrPH  
Bette Caan, DrPH
Co-Investigator
​​
Julie A. Schmittdiel, PhD  
Julie A. Schmittdiel, PhD
Co-Investigator
​​
Noelle T. Blick  
Joseph Young, MD
Co-Investigator​
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